COVID-19 is an emerging, rapidly evolving situation. [(accessed on 29 June 2020)]; Available online. h�bbd```b``Z "��I&�� ,�"Y��Im0i"�&g��3�$c�ش� 2'H��Ug`ڸ$������o� ~l+ -. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. PMID: 32825444 DOI: 10.3390/ijms21176002 Abstract At the moment, there are no U.S. Food and Drug Administration (U.S. FDA)-approved drugs for the treatment of COVID-19, although several antiviral drugs are available for repurposing. Drugs and the Pharmaceutical Sciences Series. endstream endobj startxref is available on our Permission Requests page. If you are the author of this article you do not need to formally request permission USA.gov. Many of these drugs suffer from polymorphic transformations with changes in the drug's safety and efficacy; many are poorly soluble, poorly bioavailable drugs. NLM GSK2838232; acyclovir; antiviral API-ILs; cocrystals; ionic liquids of active pharmaceutical ingredients (API-ILs); pharmaceutical salts; polymorphism; solubility. E-mail: NIH 2020 Sep 4;9(9):578. doi: 10.3390/antibiotics9090578. We advocate that the industry should consider the advantages of API-ILs which could be the genesis of disruptive innovation and believe that in order for the industry to grow and develop, the industry should be comfortable with a certain element of risk because progress often only comes from trying something different. In addition, the weight average molecular weight (MW) of the chitin has the potential to be controlled by shrimp age/size. Gabriela Gurau is an academic associate in green chemistry at McGill University, Montreal, Canada, and chief financial officer at 525 Solutions. In pursuit of bioplastics which require a controlled biopolymer molecular weight, consistency, and supply, we have examined the chitin in the molts of farm raised Hybrid (H1) Pacific whiteleg shrimp (Litopenaeus vannamei) by collecting the molts during the shrimp growth cycle, sorting by shrimp average body weight (ABW), and extracting the chitin from the molts using the ionic liquid (IL) 1-ethyl-3-methylimidazolium acetate ([C2mim][OAc]). This site needs JavaScript to work properly.  |  Box 2206, Tuscaloosa, AL 35403, USA E-mail: Robin.Rogers@525Solutions.com.  |  or in a thesis or dissertation provided that the correct acknowledgement is given %PDF-1.6 %���� Information about reproducing material from RSC articles with different licences Org. Recycling Old Antibiotics with Ionic Liquids. Please enable it to take advantage of the complete set of features! Robin D. Rogers BioSketch: Dr. Robin D. Rogers is President, Owner, and Founder of 525 Solutions, Inc., in Tuscaloosa, AL USA and a Research Professor at The University of Alabama.

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